Biomedical Research
Cures Collaborative
Finding a functional cure is central to solving single ventricle heart disease, but no one scientist, lab, or even field can do it alone.
The Additional Ventures Cures Collaborative is a multidisciplinary team of nine investigators across eight institutions brought together to develop a regenerative medicine solution that can improve cardiac function and reduce poor outcomes.
A Multidisciplinary, Collaborative Approach
We’re fostering outstanding and accelerated science by bringing together a diverse team of investigators with complementary expertise and resources across basic, translational, and engineering sciences in concert with medical knowledge — all united by a common goal.
Scientific Goals
Together, team members determine overall research direction, developing group and individual research plans every six months as projects advance and discoveries are made.
The inaugural Cures Collaborative is focused on tissue engineering approaches that create cardiac function with a better risk-benefit profile than is currently achieved, for both the post-natal and Fontan population.
Cures Collaborative Members
The Cures Collaborative is composed of nine investigators, with leadership support from Additional Ventures and administrative support through University of Central Florida. The Cures Collaborative Co-Directors Dr. Chris Breuer and Dr. Tain-Yen Hsia provide organizational and strategic support.
Over the next five years, the team will work together with the members of their labs to accelerate the pace of science using an integrated approach that tackles the problem from all sides.
Tain-Yen Hsia, MD (Coordinator)
Pediatric Cardiothoracic Surgeon and Professor of Surgery
Arnold Palmer Hospital for Children and University of Central Florida
Chris Breuer, MD (Co-Coordinator)
Director, Center for Regenerative Medicine
Nationwide Children’s Hospital
Nicole Dubois, PhD
Associate Professor
Cell, Developmental and Regenerative Biology
Icahn School of Medicine at Mount Sinai
Stacey Rentschler, MD, PhD
Associate Professor of Medicine, Cardiovascular Division
Washington University in St. Louis
Michael Davis, PhD
Professor and Associate Chair of Biomedical Engineering, Director, Children’s Heart Research and Outcomes Center
Emory University and Georgia Tech
Mark Skylar Scott, PhD
Assistant Professor of Bioengineering
Stanford University
Alison Marsden, PhD
Professor, Departments of Pediatrics and Bioengineering, and by courtesy, Mechanical Engineering
Stanford University
Adam Feinberg, PhD
Professor, Department of Biomedical Engineering, Department of Materials Science & Engineering
Carnegie Mellon University
Jay Humphrey, PhD
John C. Malone Professor of Biomedical Engineering and Department Chair
Yale University (School of Engineering and Applied Science, School of Medicine)